Major Role Of Drug Interactions In Pharmacy

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There are thousands of prescription drugs, with more and more new medications introduced every year, and hundreds of dietary supplements and herbal products available in pharmacies and stores. Consumers should be aware of the dangers of combining certain drugs and other substances, including supplements, herbal products, foods, and beverages. A drug interaction is a reaction between two (or more) drugs or between a drug and a food, beverage, or supplement. Taking a drug while having certain medical conditions can also cause a drug interaction. For example, taking a nasal decongestant if you have high blood pressure may cause an unwanted reaction. A drug interaction can affect how a drug works or cause unwanted side effects.  

Not all drugs interact with each other. However, the more medications a patient takes, the more likely it is that some medications will interact with each other. With proper oversight from a doctor, it can still be possible to take multiple medications safely and avoid interactions. There are three types of interactions such as, Drug-drug interactions, Drug-food/beverage interactions, Drug-disease interactions.  

Drug-drug interactions occur when two or more drugs react with each other. This drug-drug interaction may cause you to experience an unexpected side effect. For example, mixing a drug you take to help you sleep (a sedative) and a drug you take for allergies (an antihistamine) can slow your reactions and make driving a car or operating machinery dangerous.  Drug-food/beverage interactions result from drugs reacting with foods or beverages. For example, mixing alcohol with some drugs may cause you to feel tired or slow your reactions.  Drug-condition interactions may occur when an existing medical condition makes certain drugs potentially harmful. For example, if you have high blood pressure you could experience an unwanted reaction if you take a nasal decongestant.

Drug interactions can occur in several different ways:  A pharmacodynamics interaction occurs when two drugs given together act at the same or similar receptor site and lead to a greater (additive or synergistic) effect or a decreased (antagonist) effect.  pharmacokinetic interaction may occur if one drug affects another drug’s absorption, distribution, metabolism, or excretion.   

Drug interactions are important to check for because they can, affect how your medication works by changing levels of the drug in your blood, put you at risk for side effects and toxicity, and worsen a medical condition you may already have. Personal traits can play a role in whether a drug interaction will happen and if it will be harmful. Specifics about your drugs, including dosage, formulation, and how you take them, can also make a difference. The following factors of an individual’s medical history influence possible drug interactions: Genetics, Weight, Age, Sex (male or female), Lifestyle (diet and exercise), how long the drug is in your body, how long you’ve been taking the drug, Dose, how the drug is taken or administered, formulation, the order in which medications are taken.

Possible side effects from interactions include: Drowsiness, Rapid heartbeat, Changes in blood pressure, Bleeding, Flushing, Diarrhea, Ruptured Achilles tendon, Coma, Death.

On the occasion of its 3 years, Successful Journey, Journal of Clinical Pharmacology and Toxicology decided to provide a partial waiver on its article processing charges to promote quality research from across the nations of the globe to encourage the latest research in the field of Infections, Diseases and Medicine. Journal of Clinical Pharmacology and Toxicology also planning to release a special issue on its new approaches.

Regards

Mary Wilson

Editorial office

Journal of Clinical Pharmacology and Toxicology

E-mail: pharmatoxicol@eclinicalsci.com

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